What Are The Risks from Bisphosphonates?

Research shows that oral bisphosphonates are safe and effective for most people, but there is some evidence of increased risk of osteonecrosis of the jaw and esophogeal cancer. What are the risks from Fosamax, Actonel and similar drugs?

Cells Affected by Bisphosphonates

Several readers have wanted to know what exactly bisphosphonates do on a cellular level. Read the brief description here of cells affected by bisphosphonates.

Doctor and patient discussing over reports

Four Key Traits in an Osteoporosis Doctor

Finding the right doctor to treat osteoporosis is a big decision. It may be the most important decision you will make in managing your condition. But that decision can be harder than for other diseases. If you have cancer, you go to an oncologist. If you tear a ligament in your knee, you go to

Cavities and Bisphosphonates

Houston dentist Spiker Davis recently wrote that he had seen a lot of cavities (caries) in patients taking oral bisphosphonates. These patients were long-term patients with good dental health: I am a general dentist and I have noticed lately that I have 3 patients who haven’t had a cavity in 20-30 years and all of

Cells Affected by Fosamax

Some visitors to this site have asked which cells are affected by Fosamax and other bisphosphonates. Since all bisphosphonates act on the same fundamental cells, we can look at them as a whole and apply what we know about bisphosphonates in general to Fosamax in particular and vice-versa. Osteoblasts Versus Osteoclasts We have two basic

Complementary Treatments for Osteoporosis

Indisputable research has shown that bisphosphonates such as Fosamax increase bone strength and density and strength, reduce the incidence of fractures and, when taken orally in normal doses for treating osteoporosis carry very low risk. People seeking alternatives to Fosamax should instead think in terms of complements to Fosamax and should consult their physician. Still,

Osteonecrosis of the Jaw and Fosamax Risks

Fosamax (generic name alendronate) is the most popular drug of a class of drugs called bisphosphonates that are used to treat a variety of conditions affecting the bones. Fosamax itself is primarily prescribed to combat osteoporosis, bone loss that makes the bones fragile, and osteopenia, a less severe thinning of the bones (full discussion of